Toxic epidermal necrosis - Chefo Ea Epidermal Necrosis
☆ Liphethong tsa 2022 Stiftung Warentest tse tsoang Jeremane, khotsofalo ea bareki ka ModelDerm e ne e le tlase hanyane ho feta lipuisano tse lefelloang tsa telemedicine.
Ho lahleheloa ke letlalo ka mokhoa oa Chefo Ea Epidermal Necrosis (Toxic epidermal necrosis)
References
Stevens-Johnson Syndrome (SJS) le Toxic Epidermal Necrolysis (TEN) ke maemo a sa tloaelehang moo letlalo le nang le necrosis le ho tšolloa ho hoholo. Mabapi le phekolo, cyclosporine e sebetsa haholo bakeng sa SJS, ha motsoako oa intravenous immunoglobulin (IVIg) le corticosteroids o sebetsa hantle bakeng sa linyeoe tsa SJS le TEN.
Stevens-Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) are rare diseases that are characterized by widespread epidermal necrosis and sloughing of skin. Regarding treatment, cyclosporine is the most effective therapy for the treatment of SJS, and a combination of intravenous immunoglobulin (IVIg) and corticosteroids is most effective for SJS/TEN overlap and TEN.
Stevens-Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) are rare diseases that are characterized by widespread epidermal necrosis and sloughing of skin. Regarding treatment, cyclosporine is the most effective therapy for the treatment of SJS, and a combination of intravenous immunoglobulin (IVIg) and corticosteroids is most effective for SJS/TEN overlap and TEN.
Toxic epidermal necrolysis (TEN) ke karabelo e tebileng ea letlalo e bakoang ke meriana e itseng le ts'ebetso ea tsamaiso ea 'mele ea ho itšireletsa mafung, e leng se etsang hore ho be le sekhahla se seholo sa letlalo le ka ntle (epidermis) , se amang karolo e fetang 30% ea' mele. TEN e na le palo ea batho ba shoang e fetang 20%, hangata ka lebaka la tšoaetso le bothata ba ho hema. Ho emisa meriana e bakang karabelo, ho fana ka tlhokomelo e tšehetsang, le ho sebelisa phekolo e eketsehileng ho ka ntlafatsa sephetho. Liphuputso tsa morao tjena li bontšitse hore lithethefatsi tse kang cyclosporine, tumor necrosis factor alpha inhibitors, le motsoako oa intravenous immune globulin le corticosteroids li ka thusa, ho itšetlehile ka liteko tse laoloang ka mokhoa o sa reroang le litlhahlobo tsa lithuto tse ngata.
Toxic epidermal necrolysis (TEN) is a serious skin reaction caused by certain medications and immune system activity, resulting in large-scale detachment of the outer skin layer (epidermis), affecting more than 30% of the body's surface. TEN has a mortality rate of over 20%, often due to infections and breathing difficulties. Stopping the medication causing the reaction, providing supportive care, and using additional treatments can improve the outcome. Recent studies have shown that drugs like cyclosporine, tumor necrosis factor alpha inhibitors, and a combination of intravenous immune globulin and corticosteroids can be helpful, based on randomized controlled trials and analyses of multiple studies.
Toxic epidermal necrolysis (TEN) is a serious skin reaction caused by certain medications and immune system activity, resulting in large-scale detachment of the outer skin layer (epidermis), affecting more than 30% of the body's surface. TEN has a mortality rate of over 20%, often due to infections and breathing difficulties. Stopping the medication causing the reaction, providing supportive care, and using additional treatments can improve the outcome. Recent studies have shown that drugs like cyclosporine, tumor necrosis factor alpha inhibitors, and a combination of intravenous immune globulin and corticosteroids can be helpful, based on randomized controlled trials and analyses of multiple studies.
Recent Advances: There is improved understanding of pain and morbidity with regard to the type and frequency of dressing changes. More modern dressings, such as nanocrystalline, are currently favored as they may be kept in situ for longer periods. The most recent evidence on systemic agents, such as corticosteroids and cyclosporine, and novel treatments, are also discussed.
Sesosa se tloaelehileng haholo ke meriana e itseng e kang lamotrigine, carbamazepine, allopurinol, lithibela-mafu tsa sulfonamide, le nevirapine. Lintho tse kotsi li kenyelletsa HIV le systemic lupus erythematosus. Kalafo hangata e etsahala sepetlele joalo ka phaposing ea batho ba cheleng kapa phaposing ea batho ba kulang haholo.
○ Kalafo
Ena ke lefu le tebileng, kahoo haeba molomo oa hao kapa molomo oa hao o amehile kapa letlalo la hao le e-ba le makhopho, bona ngaka ea hau kapele kamoo ho ka khonehang.
Lithethefatsi tse belaetsang li lokela ho khaotsa. (mohlala, lithibela-mafu, li-non-steroidal anti-inflammatory drugs)